然而,传统类器官培养尚有一些技术瓶颈限制其应用

类器官芯片技术可以将类器官和器官芯片技术优势互补,类器官技术可以提高器官芯片技术中细胞来源层面的仿生性。大橡科技充分利用两种技术的优势,形成类器官芯片平台具有如下优势和特征:

Reference

[1] Method of the Year 2017: Organoids. Nat. Methods, 2018, 15, 1.

[2] Modeling development and disease with organoids. Cell, 2016, 165, 1586-1597.

[3] Engineering human islet organoids from iPSCs using an organ-on-chip platform. Lab Chip, 2019,19, 948-958.

[4] Organoid-on-a-chip and body-on-a-chip systems for drug screening and disease modeling. Drug Discov. Today.  2016,21,1399-1411.-a-chip systems for drug screening and disease modeling. Drug Discov. Today. 2016,21,1399-1411.